Assessment of rate of absorption in bioequivalence studies
β Scribed by Leon Aarons
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 259 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0022-3549
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## Objective: Patients with epilepsy are often concerned that switching between brand-name and generic formulations of antiepilepsy drugs (aeds) may cause clinically significant changes in plasma drug concentrations. we assessed bioequivalence (be) studies for approved generic aeds to evaluate us f
Digitoxin, acetyl digoxin, digoxin, and lanatoside C were administered orally to unanesthetized cats in single fatal doses. Physical state of subdivision and lipoid solubility appeared to modify rate of absorption. Di itoxin, acetyl digoxin, and digoxin were rather uniformly and nearly completely at