Increased chromosome 20 copy number dete
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James H. Barks; Floyd H. Thompson; Raymond Taetle; Jin-Ming Yang; John F. Stone;
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Article
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1997
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John Wiley and Sons
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English
β 150 KB
π 1 views
DNA amplification is an important mechanism of tumor progression that allows cancer cells to up-regulate the expression of critical genes such as oncogenes and genes conferring drug resistance. Recent studies using comparative genomic hybridization (CGH) revealed increased DNA copies of 20q sequence