Permeability data from MDR1-MDCKII and PAMPA-BBB assays were compared to data from in situ brain perfusion to evaluate the accuracy of in vitro assays in predicting in vivo blood-brain barrier (BBB) permeability. PAMPA-BBB significantly correlated to in situ brain perfusion, however, MDR1-MDCKII had
Assessment of Blood–Brain Barrier Permeability Using theIn SituMouse Brain Perfusion Technique
✍ Scribed by Rong Zhao; J. Cory Kalvass; Gary M. Pollack
- Book ID
- 106493757
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 189 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0724-8741
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