Assessment of [11C]-L-Methionine Transport into the Human Brain
β Scribed by O'Tuama, Lorcan A.; Guilarte, Tomas R.; Douglass, Kenneth H.; Wagner, Henry N.; Wong, Dean F.; Dannals, Robert F.; Ravert, H. T.; Wilson, A. A.; LaFrance, Norman D.; Bice, Alden N.
- Book ID
- 109870036
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 279 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0271-678X
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Images obtained by X-ray CT, brain scintigraphy (99mTc-DTPA) and positron emission tomography (PET) with [11C-methyl]-L- and D-methionine in a case of malignant glioma are presented, showing good agreement of PET and CT findings, in particular nearly identical localization of L- and D-methionine acc
The routine measurement of L-[methyl-11C]methionine in human plasma after i.v. injection of the tracer is described. The protein-free plasma metabolites of the tracer were analyzed using a cation-exchange column (Aminex A-6) eluted with a pH 4.25 citrate buffer. The ratios of L-[methyl-11C]methionin