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Assessing the Structural Stability of Designed β-Hairpin Peptides in the Cytoplasm of Live Cells

✍ Scribed by Zihao Cheng; Robert E. Campbell


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
297 KB
Volume
7
Category
Article
ISSN
1439-4227

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β-Hairpin stabilization in a 28-residue
✍ R. A. G. D. Silva; Simon A. Sherman; Timothy A. Keiderling 📂 Article 📅 1999 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 161 KB 👁 1 views

The beta-subunit of the human chorionic gonadotropin (hCG) hormone, which is believed to be related to certain types of cancer, contains three hairpin-like fragments. To investigate the role of beta-hairpin formation in the early stages of the hCGbeta folding, a 28-residue peptide with the sequence