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Assessing Genetic Association with Human Survival at Multi-Allelic Loci

✍ Scribed by Qihua Tan; G. De Benedictis; A.I. Yashin; L. Bathum; L. Christiansen; J. Dahlgaard; N. Frizner; W. Vach; J.W. Vaupel; K. Christensen; T.A. Kruse


Book ID
111573028
Publisher
Springer
Year
2004
Tongue
English
Weight
107 KB
Volume
5
Category
Article
ISSN
1389-5729

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DNA samples from tumors and paired normal tissues from 48 patients with prostate cancer (stage B, I 6 cases; stage C, I 4 cases; stage D, I 8 cases) were examined with 26 polymorphic markers spanning chromosome 10. Allelic losses were observed in I7 of the 46 cases (37%) that were informative with a