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Assessing epidermal growth factor receptor expression in tumours: What is the value of current test methods?

✍ Scribed by A.P. Dei Tos; I. Ellis

Book ID
116428554
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
168 KB
Volume
41
Category
Article
ISSN
0959-8049

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## Abstract The epidermal growth factor receptor (EGFR) has previously been detected in the nucleus of cancer cells and primary tumors. We have reported that EGFR translocates from the plasma membrane to the nucleus. Accumulation of nuclear EGFR is linked to increased DNA synthesis and proliferatio