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Assay of human plasma for nortriptyline by radioacetylation and thin-layer chromatography

โœ Scribed by Francis R. Zuleski; Arthur Loh; Frederick J. Di Carlo


Book ID
108335683
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
335 KB
Volume
132
Category
Article
ISSN
1873-3778

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A thin-layer chromatographic (TLC) method is described for the assay of the anti-epileptic drug, valproic acid, in plasma. The use of high-performance (HPTLC) plates gave sensitive detection limits (4.87 micrograms ml-1) for derivatives of valproic acid and the reproducibility on the same or differe