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Aspirin Use is Associated with Lower Prostate Cancer Risk in Male Carriers of BRCA Mutations

✍ Scribed by Matthew Cossack, Cameron Ghaffary, Patrice Watson…

Book ID: 120703773
Publisher: Springer
Year: 2013
Tongue: English
Weight: 133 KB
Volume: 23
Category: Article
ISSN: 1059-7700
DOI: 10.1007/s10897-013-9629-8

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## Abstract Dysregulation of apoptosis plays an important role in carcinogenesis. Therefore, apoptosis‐associated genes like the __death receptor 4__ (__DR4, TRAIL‐R1__) are interesting candidates for modifying the penetrance of breast and ovarian cancer in carriers of __BRCA1__ and __BRCA2__ mutat