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Aspirin induces apoptosis in YD-8 human oral squamous carcinoma cells through activation of caspases, down-regulation of Mcl-1, and inactivation of ERK-1/2 and AKT

โœ Scribed by In-Sook Park; Jeong-Rang Jo; Hua Hong; Ki-Young Nam; Jong-Bae Kim; Sang-Hee Hwang; Mi-Sun Choi; Nam-Hee Ryu; Hyun-Jung Jang; Sang-Han Lee; Chin-Soo Kim; Tae-Geon Kwon; Gy-Young Park; Jong-Wook Park; Byeong-Churl Jang


Book ID
116920215
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
481 KB
Volume
24
Category
Article
ISSN
0887-2333

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## Abstract Under normal culture conditions, cells adhere to culture dish, spread out, proliferate, and finally cover all areas and reach confluence. During the confluent stage, cell proliferation ceases and differentiation is enhanced. Meanwhile, cell death also appears as the monolayer confluence