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Aspirin increases the expression of dna mismatch repair proteins in human colon cancer cells

✍ Scribed by Goel, Ajay; Chang, Dong K; Ricciardiello, Luigi; Chauhan, Dharam P; Boland, C. Richard

Book ID
122857553
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
180 KB
Volume
118
Category
Article
ISSN
0016-5085

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DNA mismatch repair (MMR) is essential for genome stability and inheritance of a mutated MMR gene, most frequently MSH2 or MLH1, results in cancer predisposition known as Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC). Tumors that arise through MMR deficiency show instability at