Aspersitin-a new metabolite of aspergillus parasiticus
✍ Scribed by George Büchi; Manuel A. Francisco; William V. Murray; Traudel Kachholz; Arnold L. Demain; John F. Blount
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 182 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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In the course of our lnvestlgatlon on fungal metabolltes, we have Isolated a new metabolite, which we have named sydowlc acid (I), from AspergzlZus sydowz (Balnler et Sartory) Thorn et Church. We wish to report on the method of lsolatlon and chemical structure of this metabollte.
The extraction and fractionation of toxic maize-meal cultures of Asuergillus ustus CSIR 1128, guided by bio-assay in ducklings, led to the isolation of austsmide (I) as one of the toxic metabolites. The structural elucidation of I is reported herein. 2o" Austamide, [n]D + 152' (2 1, EtOH) is a yel