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Aspergillusmelleusprotease-catalyzed peptide synthesis using the carbamoylmethyl ester as an acyl donor in 1,1,1,3,3,3-hexafluoro- 2-propanol/N,N-dimethylformamide

✍ Scribed by Toshifumi Miyazawa; Makoto Hiramatsu; Takashi Murashima; Takashi Yamada


Book ID
110403962
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
72 KB
Volume
24
Category
Article
ISSN
0141-5492

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The active ester N-fmoc-3-O-[Ac4-Ξ±-D-Man
✍ Anita Ma. Jansson; Morten Meldal; Klaus Back πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 French βš– 276 KB

The active ester ilP-Rnoc-3-o\_IAc~~-o-Manp-(l~2)-Ac~ar-D-Manpl-J-~r-O-Pfp (6) was synthesized by direct condensation of Aqor-D-Mmp-(l-2)-Ac=ar-D-h&p-Br (4) with l+noc-Thr-0-m (5) and used as a buikiing block in an automated continwus-flow solid-phase synthesis of an 0-glycosylated heptadeca amino a