Aspects of sample dispersion for optimizing flow-injection analysis systems

✍ Scribed by Takashi Korenaga

• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 931 KB
• Volume: 261
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(92)80236-z

✦ Synopsis

Solute dispersion of an injected sample plug was studied by using an experimental apparatus with ideal lammar flow m order to develop a hydrodynamic model for the design of sensitwe and precise flow-injection analysis systems The dispersion behaviour of the sample slug under different manifold conchtions was first studied m detail to evaluate the effects of various operating conditions such as tube radius, tube length, flow-rate and molecular diffusion coefficient of sample solute The capillary flow propertIes were also exammed for some commercial micropumps to select the most suitable pumping method Mwng profiles and baseline stability m short, straight tubes were mvestlgated A double-plunger micropump having a hnear cam mechamsm and a fast, short reciprocation time was proposed to obtain smoother mlxlng and more stable pumping with good reproduck& Complete nuxmg and low flow-rate pumping are strongly desired for reliable flow-injection methods for Industrial process use, blosensmg devices for protem and enzyme bioassays require lower consumption of valuable reagents