Messenger RNA purified from the anti hemin monoclonal antibody (1D3) secreting hybridoma was amplified by RT-PCR and the nueleotide and amino acid sequences of the antibody were determined. The role of complementarity determining regions (CDRs) in porphyrin recognition and its immunochemical feature
✦ LIBER ✦
Aspartate Isomerization in the Complementarity-Determining Regions of Two Closely Related Monoclonal Antibodies †
✍ Scribed by Wakankar, Aditya A.; Borchardt, Ronald T.; Eigenbrot, Charles; Shia, Steven; Wang, Y. John; Shire, Steve J.; Liu, Jun L.
- Book ID
- 126951678
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 277 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0006-2960
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Immunochemical Features of Complementari
✍
Emi Hifumi; Fumiko Morihara; Masanori Ishimaru; Keiko Morikawa; Kosuke Shimizu;
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
English
⚖ 130 KB
Characterization of the Isomerization Pr
✍
Alavattam Sreedhara; Armando Cordoba; Qing Zhu; Jeanne Kwong; Jun Liu
📂
Article
📅
2011
🏛
Springer US
🌐
English
⚖ 589 KB
Isomerization of an Aspartic Acid Residu
✍
Cacia, Jerry; Keck, Rodney; Presta, Leonard G.; Frenz, John
📂
Article
📅
1996
🏛
American Chemical Society
🌐
English
⚖ 461 KB
Display of somatostatin-related peptides
✍
Peter J. Simon; Kevin C. Brogle; Baiyang Wang; Donald J. Kyle; Daniel A. Soltis
📂
Article
📅
2005
🏛
Elsevier Science
🌐
English
⚖ 642 KB
The function of conserved amino acids in
✍
Antonio Nakouzi; Arturo Casadevall
📂
Article
📅
2003
🏛
Elsevier Science
🌐
English
⚖ 283 KB
Succinimide formation at Asn 55 in the c
✍
Boxu Yan; Sean Steen; David Hambly; John Valliere-Douglass; Tim Vanden Bos; Scot
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 354 KB
We investigated the formation and stability of succinimide, an intermediate of deamidation events, in recombinant monoclonal antibodies (mAbs). During the course of an analytical development study of an IgG1 mAbs, we observed that a specific antibody population could be separated from the main produ