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Asmarines A-C; Three novel cytotoxic metabolites from the marine sponge Raspailia sp.

✍ Scribed by Tesfamariam Yosief; Amira Rudi; Zafra Stein; Israel Goldberg; Garcia M.D. Gravalos; Michael Schleyer; Yoel Kashman

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
292 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

Three novel nitrogen-containing metabolites, asmarines A-C (1 -3) together with two known diterpenes, zaatirin and chelodane were isolated from the Red Sea sponge Raspailia sp. collected in the Dahlak archipelago, Eritrea. The structure of the three new compounds and the known zaatirin and chelodane were established by spectroscopic analysis including X-ray diffraction analysis for asmarine A. Asmarines A-C are cytotoxic to a few human cancer cells.

πŸ“œ SIMILAR VOLUMES

Callipeltosides B and C, two novel cytot
Callipeltosides B and C, two novel cytotoxic glycoside macrolides from a marine lithistida sponge Callipelta sp.
✍ Angela Zampella; M.Valeria D'Auria; Luigi Minale; CΓ©cile Debitus πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 316 KB

Following the characterization of callipeltoside A (1), the first member of a novel class of marine glycoside macrolides, two more bioactive constituents, callipeltoside B (2) and C(3), were isolated from Callipelta sp. in very low amounts. The structures, assigned on the basis of spectral analysis,