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[ASCRIT] Antisense chemoradioimmunotherapy consisting of anti-POEM (Arg-Gly-Asp) scFv linked onto high-energy radioisotopes, vinorelbine-tartrate and 21-nucleotide double-stranded siRNA targeted to DNMT1 induce apoptosis in metastatic breast cancer (MBC) characterized by hypermethylated p53, p16, RASSF1A, RAR-b2, BRCA2, H1C1, ESRI1, CDH1, Trbeta1, GSTP1, CCND2 and overexpression of bcl-2, cdc25c, Raf-1 and α8β1 integrin

✍ Scribed by J Giannios, P Lambrinos, E Maragudakis, N Alexandropoulos

Book ID
120699985
Publisher
BioMed Central
Year
2005
Tongue
English
Weight
618 KB
Volume
7
Category
Article
ISSN
1465-5411

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