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Ascorbate Affects Proliferation of Guinea-pig Vascular Smooth Muscle Cells by Direct and Extracellular Matrix-mediated Effects

✍ Scribed by Vadim O. Ivanov; Svetlana V. Ivanova; Aleksandra Niedzwiecki

Book ID: 115632542
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 205 KB
Volume: 29
Category: Article
ISSN: 0022-2828
DOI: 10.1006/jmcc.1997.0555

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## Abstract Interactions among growth factors, cells, and extracellular matrix regulate proliferation during normal development and in pathologies such as atherosclerosis. SPARC (secreted protein, acidic, and rich in cysteine) is a matrix‐associated glycoprotein that modulates the adhesion and prol