Proteases have been postulated to account for the progressive disappearance of matrix proteoglycans in osteoarthritic (OA) cartilage. The digestion of endogenous proteoglycans by neutral proteases in human OA cartilage homogenates has been measured and compared with that of normal age-matched contro
Aryl sulfatase activities in normal and pathologic human articular cartilage
β Scribed by Dr Edith R. Schwartz; Roy C. Ogle; Roby C. Thompson
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 841 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Previous laboratory measurements showed topographical variation in the properties of articular cartilage in several animal species and in humans. In this study we characterize for the first time the topographical variation of the stiffness of the human knee articular cartilage in vivo using a novel
## Abstract The study was designed to determine the contents and distributions of the proteoglycans decorin and biglycan in adult human femoral condylar cartilage and whether these may change in osteoarthritis. New radioimmunoassays were established using peptides representing the aminoβterminal 21