Aryl radical-initiated cyclizations: Effect of aryl substituents on ring-size

✍ Scribed by Kathlyn A. Parker; Denice M. Spero; Karen C. Inman

• Book ID: 104218736
• Publisher: Elsevier Science
• Year: 1986
• Tongue: French
• Weight: 182 KB
• Volume: 27
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)84654-7

✦ Synopsis

The pmence of a mdical rtabilizing group on the aql ring can lead to ring-expanded products.

Although radical cyclisation methodology is presently the subject of much attention by the synthetic chemistry community,1 studies of cyclizations initiated by aryl radicals2 have not been extensive nor have such cyclizations been exploited for total synthesis.