## Abstract Aryl hydrocarbon hydroxylase (AHH) inducibility was studied in cultured lymphocytes from 21 healthy control subjects and from 15 lung cancer patients selected for radiation therapy. AHH inducibility of the patients was measured prior to, during and at the end of radiation therapy. Four
Aryl hydrocarbon hydroxylase inducibility and lymphoblast formation in lung cancer patients
β Scribed by R. Prasad; Dr. N. Prasad; J. E. Harrell; J. Thornby; J. H. Liem; P. T. Hudgins; J. Tsuang
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 423 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0020-7136
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β¦ Synopsis
Abstract
Aryl hydrocarbon hydroxylase (AHH) inducibility and lymphoblast formation were studied in lymphocytes from healthy control subjects and from lung cancer patients undergoing radiotherapy. The relationship between AHH inducibility and percentage lymphoblasts was statistically significant only for the preβtreatment patients (r = 0.598; p<0.05). In the control group and in patients undergoing radiotherapy the correlation between AHH inducibility and lymphoblast formation was positive but statistically it was not significant. Our data do not suggest a linear relationship between AHH inducibility and lymphoblast formation.
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The inducibility of aryl hydrocarbon hydroxylase (AHH) activity in peripheral mitogen-treated lymphocytes, and of AHH and other monoxygenase activities in lung samples, was studied in 41 patients-34 with pulmonary carcinoma, 4 with a benign lung tumour and 3 with chronic obstructive pulmonary diseas
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