Primary monolayer cultures of rat hepatocytes at confluence were exposed to an exogenously added source of superoxide, and its influence on collagen synthesis was examined. Superoxide was generated by the addition of dihydroxyfumarate to the culture medium. Exposure of hepatocytes to dihydroxyfumara
Increased aryl hydrocarbon hydroxylase and prolyl hydroxylase activities in lung organ cultures exposed to benzo[a]pyrene
β Scribed by M.Zamirul Hussain; Si Duk Lee; Rajendra S. Bhatnagar
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 290 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0300-483X
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## Abstract Aryl hydrocarbon (benzo(a)pyrene) hydroxylase (AHH) activity and metabolism of benzo(a)pyrene to waterβsoluble products were measured in cultures of body fibroblasts and kidney epithelial cells from different human embryos. AHH activity at 24 h after treatment with or without benz(a)ant