ARYL AZIDES AS PHOTOAFFINITY LABELS. A PHOTOCHEMICAL STUDY OF SOME 4-SUBSTITUTED ARYL AZIDES
โ Scribed by Peter E. Nielsen; Ole Buchardt
- Book ID
- 114893767
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 506 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0031-8655
No coin nor oath required. For personal study only.
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## Abstract 5โNitroโ2โ[Nโ3โ(4โazidoโ2,3,5,6โtetrafluorophenyl)โpropylamino]โbenzoic acid (FAzNPPB), a photoaffinity analog of the potent epithelial chloride channel blocker 5โnitroโ2โ(3โphenylpropylamino)โbenzoic acid (NPPB) has been prepared in five steps from commercially available 4โaminoโ2,3,5,
The azidophenyl 6.7-epoxygeranyl ethers ruc4c and ruc-rld and the azidobenzoate ruc-6 were synthesized pAzidophenyl 6,7epoxygeranyl ether (rac4c) shows a high afhity to the juvenile hormone binding protein of the migratory locust, Locusro migraioria. Fast photolysis is observed upon irradiation at 2
The 1,3-cycloaddition of aryl azides to the olefinic bonds of 4- and 2-vinylpyridines has been found to yield pyridyl substituted aziridines as the main reaction products with only smaller amounts of the normally expected 1-aryl-5-pyridyl-1,2,3-triazolines. Theoretical and experimental evidence are