Artificial model for cystathionine β-synthase: construction of a catalytic cycle with a pyridoxal model compound having an ionophore function

✍ Scribed by Kazuyuki Miyashita; Hidenobu Murafuji; Hiroshi Iwaki; Eito Yoshioka; Takeshi Imanishi

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 189 KB
• Volume: 59
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(03)00665-3

✦ Synopsis

Catalytic transformation of serine-O-carbonate to S-aryl cysteine derivatives was successfully achieved in the presence of Li þ by the use of a pyridoxal model compound having an ionophore function, which is the first example mimicking cystathionine b-synthase, artificially.