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Artificial diiron proteins: From structure to function

✍ Scribed by Jennifer R. Calhoun; Flavia Nastri; Ornella Maglio; Vincenzo Pavone; Angela Lombardi; William F. DeGrado

Publisher: Wiley (John Wiley & Sons)
Year: 2005
Tongue: English
Weight: 661 KB
Volume: 80
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.20230

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✦ Synopsis

Abstract

De novo protein design provides an attractive approach for the construction of models to probe the features required for the function of complex metalloproteins. These minimal models contain the essential elements believed necessary for activity of the protein. In this article, we summarize the design, structure determination, and functional properties of a family of artificial diiron proteins. © 2005 Wiley Periodicals, Inc. Biopolymers (Pept Sci), 2005

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