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Artificial chromosomes in yeast

โœ Scribed by Elizabeth H. Blackburn


Book ID
113288208
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
621 KB
Volume
1
Category
Article
ISSN
0168-9525

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Transfer of yeast artificial chromosomes
โœ Clare Huxley; Andreas Gnirke ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 729 KB

Human DNA can he cloned as yeast artificial chromosomes (YACs), each of which contains several hundred kilobases of human DNA. This DNA can be manipulated in the yeast host using homologous recombination and yeast selectable markers. In relatively few steps it is possible to make virtually any chang