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Arterial and venous blood sampling in pharmacokinetic studies: Griseofulvin

✍ Scribed by Mei-Ling Chen; Gilbert Lam; Myung G. Lee; Win L. Chiou


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
410 KB
Volume
71
Category
Article
ISSN
0022-3549

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The pharmacokinetics of azosemide were evaluated simultaneously using both arterial and venous plasma data in six rabbits after a rapid 5 s intravenous bolus dosing. Initial arterial to venous ratios at 5 s after injection were the highest with values of 81 \* 1,67 -3, 58-7,530,2660, and 10.5 for ra