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Arsenic Induces Overexpression of Growth Factors in Human Keratinocytes

✍ Scribed by Dori R. Germolec; Takahiko Yoshida; Kevin Gaido; James L. Wilmer; Petia P. Simeonova; Fujio Kayama; Florence Burleson; Wumin Dong; Robert W. Lange; Michael I. Luster


Book ID
112266257
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
833 KB
Volume
141
Category
Article
ISSN
0041-008X

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## Abstract Epidermal growth factor receptor (EGFR) plays a critical role in mediating ultraviolet (UV) irradiation‐induced signal transduction and gene expression in human keratinocytes. EGFR activation results from increased phosphorylation on specific tyrosine residues in the C‐terminal intracel