Autocrine nerve growth factor in human keratinocytes
β Scribed by Pincelli, Carlo; Marconi, Alessandra
- Book ID
- 119562842
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 184 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0923-1811
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Endothelin-I (ET-1) is an endothelium-derived 21 amino acid vasoconstrictor peptide possessing two intrachain disulfide bridges. Recently it has become evident that isoforms of ET (ET-l, -2, and -3) have a wide range of pharmacological effects in various tissues and act as autocrineiparacrine factor
## Abstract Keratinocyte growth factor (KGF; also known as FGFβ7) is a wellβcharacterized paracrine growth factor for tissue growth and regeneration. However, its role in adipose tissue, which is known to undergo tremendous expansion in obesity, is virtually unknown. Given that we previously identi