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Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids

โœ Scribed by Nguyen, Thanh V.; Bekensir, Alp


Book ID
123620549
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
832 KB
Volume
16
Category
Article
ISSN
1523-7060

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Solid-state nucleophilic aromatic substi
โœ M.C. Etter; G.M. Frankenbach; J. Bernstein ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 249 KB

A facile thermally activated aromatic nucleophilic substitution reaction is shown to take place in the solid state in cccrystals of 4-chloro-3,5dinitrobenzoic acid and 4-aminobenzoic acid. The cocrystals are also made in the solid state by grinding the two acids together at room temperature.