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Are Radical Cation States Delocalized over GG and GGG Hole Traps in DNA?

✍ Scribed by Voityuk, Alexander A.


Book ID
126877081
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
104 KB
Volume
109
Category
Article
ISSN
0022-3654

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Oxidative damage to DNA by ionizing radiation, carcinogenic agents, and photosensitizers occurs predominately at guanine (G) bases, [1, 2] a result which can be rationalized by the hierarchy of in vitro oxidation potentials of the isolated nucleobases (G < A ( C,T). [3] Strand cleavage reactions, in