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Are high initial CEA and CA 19–9 levels associated with the presence of K-ras mutation in patients with metastatic colorectal cancer?

✍ Scribed by Fatih Selcukbiricik, Ahmet Bilici, Deniz Tural, Sibel Erdamar…

Book ID
120719494
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
213 KB
Volume
34
Category
Article
ISSN
1010-4283

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✍ Daniel J. Freeman; Todd Juan; Maureen Reiner; J. Randolph Hecht; Neal J. Meropol 📂 Article 📅 2008 🏛 CIG Media Group, LP. 🌐 English ⚖ 502 KB

Background: Identifying predictive biomarkers is important to optimally treat patients. This analysis evaluated the association of K-ras, BRAF, and PIK3CA gene mutations with tumor resistance to panitumumab alone. Patients and Methods: From 3 phase II panitumumab metastatic colorectal cancer (mCRC)