𝔖 Bobbio Scriptorium
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Are breast tumours resistant to tamoxifen also resistant to pure antioestrogens?

✍ Scribed by Wakeling, Alan E.

Book ID
122378572
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
766 KB
Volume
47
Category
Article
ISSN
0960-0760

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## Abstract The pure steroidal anti‐estrogens ICI 164,384 and ICI 182,780 are very potent growth inhibitors of the estrogen receptor‐positive human breast cancer cell line MCF‐7. However, long‐term treatment of MCF‐7 cells with 10^βˆ’7^ M concentrations of these compounds results in selection of prol