ARE ANTIMITOCHONDRIAL ANTIBODIES IN PRIMARY BILIARY CIRRHOSIS INDUCED BY R(ROUGH)-MUTANTS OF ENTEROBACTERIACEAE?
✍ Scribed by Stemerowicz, Roman; Möller, Bernd; Rodloff, Arne; Freudenberg, Marina; Hopf, Uwe; Wittenbrink, Christel; Reinhardt, Richard; Galanos, Chris
- Book ID
- 122388280
- Publisher
- The Lancet
- Year
- 1988
- Tongue
- English
- Weight
- 718 KB
- Volume
- 332
- Category
- Article
- ISSN
- 0140-6736
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📜 SIMILAR VOLUMES
Antimitochondrial antibodies from patients with primary biliary cirrhosis react with different mitochondrial polypeptides as demonstrated by Western blots. The IgG fractions of a patient with primary biliary cirrhosis Stage I reacting exclusively with a pair of polypeptides a t 48,000 daltons (p 48)
Antimitochondrial antibodies are markers for primary biliary cirrhosis and probably reflect a specific d e f e in immunoregulation underlying this disease. Antimitochondrial antibodies and their primary biliary cirrhods-epecific subtypes were tested before and up to 6 y m after orthotopic liver tra