✦ LIBER ✦

Are antimitochondrial antibodies of prognostic value in primary biliary cirrhosis?

✍ Scribed by Neil D. Smith; James L. Boyer

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 442 KB
Volume: 6
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.1840060433

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Antimitochondrial antibodies in acute li

Antimitochondrial antibodies in acute liver failure: Implications for primary biliary cirrhosis

✍ Patrick S. C. Leung; Lorenzo Rossaro; Paul A. Davis; Ogyi Park; Atsushi Tanaka; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 2 views

In our previous work, including analysis of more than 10,000 sera from control patients and patients with a variety of liver diseases, we have demonstrated that with the use of recombinant autoantigens, antimitochondrial autoantibodies (AMAs) are only found in primary biliary cirrhosis (PBC) and tha

Caspase induction by IgA antimitochondri

Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis

✍ Shuji Matsumura; Judy Van de Water; Patrick Leung; Joseph A. Odin; Kazuhide Yama 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 2 views

## Anti -mitochondrial antibodies (AMAs) have long been recognized as a serological hallmark of primary biliary cirrhosis (PBC). Although high titers of immunoglobulin (Ig)A AMAs are found in bile, saliva, and urine of patients, a pathogenic role for this antibody has remained elusive. Functional

Increased prevalence of antimitochondria

Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis

✍ Konstantinos N. Lazaridis; Brian D. Juran; Gwen M. Boe; Joshua P. Slusser; Mariz 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB 👁 1 views

Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disorder that can progress to cirrhosis, shortening life expectancy. PBC patients are often asymptomatic, present with biochemical cholestasis, and test positive (>90%) for antimitochondrial antibodies (AMAs) in serum. Although AMA posit

Comparative studies of antimitochondrial

Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis

✍ A Nishio; J Van de Water; P S Leung; R Joplin; J M Neuberger; J Lake; A Bjorklan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB 👁 1 views

Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by destruction of intrahepatic bile ducts. Although the pathogenesis of this disease is still unknown, high titers of antimitochondrial autoantibodies (AMA) have long been recognized in patient sera. However, little is know

Comparison of the clinical features and

Comparison of the clinical features and clinical course of antimitochondrial antibody-positive and -negative primary biliary cirrhosis

✍ P Invernizzi; A Crosignani; P M Battezzati; G Covini; G De Valle; A Larghi; M Zu 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB 👁 1 views

Reports from North America and Northern Europe have suggested that antimitochondrial antibody (AMA) negative primary biliary cirrhosis (PBC) is a distinct chronic cholestatic liver disease with high prevalence of serum non-organ-specific autoantibodies other than AMA. To evaluate if such a peculiar

Reactivities and clinical relevance of a

Reactivities and clinical relevance of antimitochondrial antibodies to four mitochondrial inner membrane proteins in sera of patients with primary biliary cirrhosis

✍ Hideo Ishii; Koji Saifuku; Professor Toshihiko Namihisa 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB 👁 1 views

Antimitochondrial antibodies are characteristically detected in sera of patients with primary biliary cirrhosis. The antigens to which the antimitochondrial antibodies in primary biliary cirrhosis sera react have been located in the mitochondrial inner membrane. We have reported on four mitochondria