A rapid, semiautomated system to quantitate and analyze leukocyte shape and locomotion was developed. Video images of moving leukocytes were obtained using a Vidicon camera mounted on a Nikon phase microscope. The video signal was either inputted directly, or indirectly via a video cassette recorder
Architecture of tissue cells the structural basis which determines shape and locomotion of cells
✍ Scribed by Jürgen Bereiter-Hahn
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 455 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0001-5342
No coin nor oath required. For personal study only.
✦ Synopsis
Shape and locomotion of tissue cells depend on the interaction of elements of the cytoskeleton, adhesion to the substrate and anintracellular hydrostatic pressure. The existence of this pressure becomes obvious from increase in cell volume on cessation of contractile forces and from observations with ultrasound acoustic microscopy. Wherever such an internal pressure is established, it is involved in generation of shape and driving force of cell locomotion. Therefore each hypothesis on cell shape and locomotion must consider this property of a living cell. Apparently different types of locomotion depend on differences in substrate adhesion and/or cytoskeleton organization.
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