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Arachidonic acid release induced by extracellular ATP in osteoblasts: role of phospholipase D

✍ Scribed by Y. Watanabe-Tomita; A. Suzuki; J. Shinoda; Y. Oiso; O. Kozawa


Book ID
117642527
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
407 KB
Volume
57
Category
Article
ISSN
0952-3278

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In a previous study, we have shown that endothelin-1 (ET-1) activates phospholipase D independently from protein kinase C in osteoblast-like MC3T3-E1 cells. It is well recognized that phosphatidylycholine hydrolysis by phospholipase D generates phosphatidic acid, which can be further degraded by pho