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Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine](sulfato)platinum(II) complexes with variable substituents in the 2-phenyl ring. 1. Synthesis and antitumor and estrogenic properties

✍ Scribed by Gust, Ronald; Burgemeister, Thomas; Mannschreck, Albrecht; Schoenenberger, Helmut

Book ID: 121322803
Publisher: American Chemical Society
Year: 1990
Tongue: English
Weight: 1019 KB
Volume: 33
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00171a031

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## Palladium(D) and platinum(II) halides with 3,6disubstituted-2,7dihydro-1,4,5thiadiazepine derivatives (L) form complexes of general formula, [MX,*L'] (L' = monohydrazone, VII). During the formation of these complexes, the thiadiazepine ring underwent hydrolytic cleavage at the carbonnitrogen doub