Approximation of RNA multiple structural alignment
✍ Scribed by Marcin Kubica; Romeo Rizzi; Stéphane Vialette; Tomasz Waleń
- Book ID
- 113699030
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 289 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1570-8667
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We consider the problem of aligning of k sequences of length n. The cost function is sum of pairs, and satisfies triangle inequality. Earlier results on finding approximation algorithms for this problem are due to Gusfield (1991) who achieved an approximation ratio of 2 -2/k, and Pevzner (1992) who
We consider a weighted generalization of multiple sequence alignment (MSA) with sum-of-pair score. MSA without weights is known to be NP-complete and can be approximated within a constant factor, but it is unknown whether it has a polynomial time approximation scheme. Weighted multiple sequence alig