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Approach to the synthesis of annonaceous acetogenins from D-glucose

✍ Scribed by Philippe Bertrand; Jean-Pierre Gesson


Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
235 KB
Volume
33
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


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In connection with the synthesis of Β’ytotoxic annonaceous acetogenin analogs, e]~ntiomerically pure threo (and erythro)-trans THF synthons have been p~epered from D-glucose. These synthons are characterized by the presence of two methoxy (or hydroxy) groups in the THF ring. each in a c/s configurati

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Three new Annonaceous acetogenins, (2,4-cis and trans)-9-hydroxy asimicinone (1), (2,4-cis and trans)squamoxinone B (2) and (2,4-cis and trans) squamoxinone C (3), were isolated from the bark of Annona squamosa with the help of countercurrent chromatography. Additionally found was isoannoreticuin (4