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Applied advanced process analytics in biopharmaceutical manufacturing: Challenges and prospects in real-time monitoring and control

✍ Scribed by Cenk Ündey; Sinem Ertunç; Thomas Mistretta; Bryan Looze

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
731 KB
Volume
20
Category
Article
ISSN
0959-1524

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In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools
✍ De Beer, T. R.M. (author);Vercruysse, P. (author);Burggraeve, A. (author);Quinte 📂 Article 📅 2009 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 755 KB

The aim of the present study was to examine the complementary properties of Raman and near infrared (NIR) spectroscopy as PAT tools for the fast, noninvasive, nondestructive and in-line process monitoring of a freeze drying process. Therefore, Raman and NIR probes were built in the freeze dryer cham