Recewcd 14 May 1980 t3C IVhfR spectra, obtamed for a number of clathrates, hydrogen-bonded complexes and polymorphic forms of hydroquinone, proved to be umquely related to the crystal structures. pquinols can easily be dlstingulshed from o-and yqumols, and hydroqumone in stolciuometric complcucs. St
Applications of Solid-State NMR to Pharmaceutical Polymorphism and Related Matters
โ Scribed by Robin K. Harris
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
Most solid-state kinetic principles were derived from those for homogenous phases in the past century. Rate laws describing solid-state degradation are more complex than those in homogenous phases. Solid-state kinetic reactions can be mechanistically classified as nucleation, geometrical contraction
Crystalline lactose was subjected to various forms of pharmaceutical processing including compaction, lyophilization, spray drying, and cryogrinding. (13)C cross polarization and magic-angle spinning (CPMAS) NMR spectra were acquired for bulk crystalline lactose as well as the processed samples. Sat