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Applications of random field theory to functional connectivity

✍ Scribed by Keith J. Worsley; J. Cao; T. Paus; M. Petrides; A.C. Evans


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
184 KB
Volume
6
Category
Article
ISSN
1065-9471

No coin nor oath required. For personal study only.

✦ Synopsis


Functional connectivity between two voxels or regions of voxels can be measured by the correlation between voxel measurements from either PET CBF or BOLD fMRI images in 3D. We propose to look at the entire 6D matrix of correlations between all voxels and search for 6D local maxima. The main result is a new theoretical formula based on random field theory for the p-value of these local maxima, which distinguishes true correlations from background noise. This can be applied to crosscorrelations between two different sets of images--such as activations under two different tasks, as well as autocorrelations within the same set of images.


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