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Applications of column-switching technique in biopharmaceutical analysis: I. High-performance liquid chromatographic determination of amitriptyline and its metabolites in human plasma

✍ Scribed by Darioush Dadgar; Anna Power


Publisher
Elsevier Science
Year
1987
Weight
675 KB
Volume
416
Category
Article
ISSN
0378-4347

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High performance liquid chromatographic
✍ Nieder, M. ;Jaeger, H. πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 488 KB

Anoptimized HPLC method forthe quantificationof metoclopramide (MCP) in human plasma and urine is described. MCP and internal standard are extracted from alkalinized substrate into diethyl ether and back-extracted into dilute acid. The analytes are separated with a ternary mobile phase at cyanopropy