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Application research of a novel designed peptide as a potential carrier

✍ Scribed by LiPing Ruan; HangYu Zhang; HanLin Luo; XiaoJun Zhao


Publisher
SP Science China Press
Year
2009
Tongue
English
Weight
740 KB
Volume
52
Category
Article
ISSN
1674-7291

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Synthesis of a template-associated pepti
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We describe the design and the Fmoc/tBu solid phase synthesis of a 20 residue long peptide containing five regularly distributed lysines. Cyclization of this peptide was achieved using BOP as coupling agent. After side-chain deprotection, all the basic residues were iodoacetylated and then allowed t