Spacer-modified polymer supports have been synthesized through the polymeric Grignard reagent method. Phosphonium-active sites were then introduced into these supports and the polymer-supported phosphonium salts were used as phase transfer catalysts for the nucleophilic substitution reactions. lnflu
Application of polymer-bound phosphonium salts as traceless supports for solid phase synthesis
β Scribed by Ian Hughes
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 210 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A calix [4]arene derivative has been anchored to carboxyl CPG and TentaGel supports by an easily cleavable ester bond and DMT groups allow a simple loading evaluation via UV-vis spectroscopy. The loading of the calixarene on TentaGel resin has also been estimated by HR-MAS NMR experiments. The poten
## Abstract Nickelβcatalyzed reactions between polymerβbound arenesulfonates and aryl Grignard reagents produce unfunctionalized biphenyls and terphenyls in good yields through reductive cleavage/crossβcoupling of the CβS bond. This novel traceless multifunctional cleavage strategy appears to be a