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Application of new molecular methods in detection of Intron 22 inversion mutation of factor VIII gene in patients with Hemophilia A

โœ Scribed by Seyed Hamid Mousavi; Seyed Alireza Mesbah Namin; Fereidoon Ala


Book ID
118430928
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
60 KB
Volume
44
Category
Article
ISSN
0009-9120

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Hemophilia A is a common X-linked bleeding disorder caused by mutations in the coagulation factor VIII gene. The entire coding and essential sequences of the factor VIII gene were generated by a combination of genomic DNA amplification and long reverse transcription-polymerase chain reaction (long R