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Application of modified ising model to the helix-coil transition of DNA molecules

✍ Scribed by M. Leung; F. C. Choo; B. Y. Tong

Publisher: Wiley (John Wiley & Sons)
Year: 1977
Tongue: English
Weight: 561 KB
Volume: 16
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.1977.360160606

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✦ Synopsis

Abstract

Equilibrium properties of heterogeneous DNA near the melting temperature T~m~ are investigated using the grand partition function. The present approach gives exact and analytical solutions. The algebraic expressions enhance a more thorough understanding of the correlation among many observed equilibrium phenomena. The following quantities have been examined: melting temperature T~m~, transition width W, partial melting curves θ~AT~ and θ~GC~, mean length of a helical segment h, and correlation length γ.

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