A series of matrix-type drug delivery devices comprising a continuous phase of microporous poly(epsilon-caprolactone) (PCL) and a dispersed phase of protein particles (gelatin) with defined size ranges (45-90, 90-125 and 125-250 microm) were produced by rapidly cooling suspensions in dry ice followe
Application of Micro- and Nano-Electromechanical Devices to Drug Delivery
β Scribed by Mark Staples; Karen Daniel; Michael J. Cima; Robert Langer
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 844 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0724-8741
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## Abstract Summary: In this work, INU, a natural polysaccharide, has been chemically modified in order to obtain new photocrosslinkable derivatives. To reach this goal, INU has been derivatized with MA thus obtaining four samples (INUβMA derivatives) as a function of the temperature and time of re