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Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders

✍ Scribed by Ole Diettrich; Kevin Mills; Andrew W Johnson; Andrej Hasilik; Bryan G Winchester


Book ID
117110186
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
164 KB
Volume
441
Category
Article
ISSN
0014-5793

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## ABSTRACT Immunofluorescence microscopy shows that unlike cytoplasmic microtubules (MT), vimentin‐type intermediate filaments (IF) are collected into ring‐shaped structures in affected fibroblasts. The altered IF organization could be observed in monolayers of polarized fibroblasts in the prolong